作者单位
摘要
北京遥感设备研究所,北京 100854
太赫兹成像雷达具有合成孔径时间短、分辨力高的优点,适用于近场探测,但由于器件成熟度相对不高,雷达系统常存在较大的系统失真,会降低信号质量;同时,系统固有延时的存在会引起距离测量误差,二者均会恶化雷达成像的质量。针对系统失真和固有延时,提出了最小二乘法估计的幅相误差补偿方法和固有延时补偿方法,并给出了系统误差的测量方法。试验测试结果表明,用该方法对系统进行补偿后能有效提高图像空间分辨力,改善图像质量。
太赫兹 近场成像 系统误差 补偿 terahertz near-field imaging system distortion compensation 
太赫兹科学与电子信息学报
2019, 17(1): 1
Author Affiliations
Abstract
1 Department of Ophthalmology, Shanxi Eye Hospital, Taiyuan 030002, P. R. China
2 Department of Ophthalmology, Xin Hua hospital affiliated to Shanghai, JiaoTong University School of Medicine, Shanghai 200092, P. R. China
3 Department of Ophthalmology, MinHang Hospital, Affiliated to Fudan University, Shanghai 201199, P. R. China
4 Shenzhen Key Laboratory for Minimal Invasive Medical Technologies, Institute of optical imaging and sensing, Graduate School at Shenzhen, Tsinghua University, Shenzhen 518055, P. R. China
5 Department of Physics, Tsinghua University, Beijing 100084, P. R. China
Surface functionalization of sensor chip for probe immobilization is crucial for the biosensing applications of surface plasmon resonance (SPR) sensors. In this paper, we report a method circulating the dopamine aqueous solution to coat polydopamine film on sensing surface for surface functionalization of SPR chip. The polydopamine film with available thickness can be easily prepared by controlling the circulation time and the biorecognition elements can be immobilized on the polydopamine film for specific molecular interaction analysis. These opera-tions are all performed under flow condition in the fluidic system, and have the advantages of easy implementation, less time consuming, and low cost, because the reagents and devices used in the operations are routinely applied in most laboratories. In this study, the specific absorption between the protein A probe immobilized on the sensing surface and human immunoglobulin G in the buffer is monitored based on this surface functionalization strategy to demonstrated its feasibility for SPR biosensing applications.
Surface plasmon resonance surface functionalization dopamine molecular interac-tion analysis 
Journal of Innovative Optical Health Sciences
2017, 10(2): 1650040

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